Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519583 | 0.91 | ALDH1A1 (0.56) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL7805754 | 0.89 | ALDH1A1 (0.55) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL11308943 | 0.88 | GAA (0.57) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL20989755 | 0.79 | MAPT (0.56) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL18155145 | 0.79 | MAPT (0.56) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL7811975 | 0.78 | ALDH1A1 (0.57) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL7465969 | 0.78 | SMN1; SMN2 (0.53) | MAPTTDP1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7808022 | 0.76 | ALDH1A1 (0.62) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL3718871 | 0.76 | MAPT (0.63) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL6151379 | 0.76 | ALDH1A1 (0.63) | MAPTTDP1LMNAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30798-E | BY REACTING 4-FLUORO-3-NITROANILINES WITH AMMONIA OR A PRIMARY OR SECONDARY AMINE | CLAIROL INCORPORATED (US) | 1981-11-17 | — | — | US | disclosed |