Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805754 | 0.95 | ALDH1A1 (0.55) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL11308943 | 0.93 | GAA (0.57) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL11308452 | 0.91 | MAPT (0.53) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL20623027 | 0.80 | GAA (0.57) | ALDH1A1TDP1MAPTMAPK1GAA | |
| SCHEMBL6151379 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL8318666 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL127252 | 0.77 | TDP1 (0.62) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL29390088 | 0.77 | TDP1 (0.62) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL27752508 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL14174537 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917531-B1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | SCHWARZKOPF GMBH HANS (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-0917531-A1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | Hans Schwarzkopf GmbH & Co. KG (DE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998001434-A1 | NEW PIPERAZINE DERIVATIVES AND OXYDATION DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1998-01-15 | — | — | WO | disclosed |