Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321162 | 0.76 | CSNK2A2 (0.50) | POLBAKR1B1MCL1 | |
| SCHEMBL11325784 | 0.74 | MCL1 (0.39) | MCL1CA12CA9 | |
| SCHEMBL11315028 | 0.73 | KMT2A (0.43) | MEN1KMT2ANPC1MCL1TP53 | |
| SCHEMBL11320518 | 0.70 | TTR (0.52) | MEN1KMT2AAKR1B1MCL1PTGDR2 | |
| SCHEMBL4989165 | 0.69 | MCL1 (0.39) | MCL1 | |
| SCHEMBL11329000 | 0.68 | MAPT (0.50) | POLBMEN1KMT2ANPC1MCL1 | |
| SCHEMBL3618120 | 0.67 | ALDH1A1 (0.50) | MEN1KMT2ANPC1MCL1 | |
| SCHEMBL11324534 | 0.65 | MCL1 (0.57) | MEN1KMT2ANPC1MCL1 | |
| SCHEMBL11313409 | 0.65 | MCL1 (0.57) | MEN1KMT2AMCL1CA12CA9 | |
| SCHEMBL11311546 | 0.65 | MAPT (0.49) | POLBMEN1KMT2ANPC1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |