Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321162 | 0.86 | CSNK2A2 (0.50) | MCL1TTRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11325753 | 0.78 | ALDH1A1 (0.41) | CSNK2A2CSNK2BCSNK2A1AHRKDM4E | |
| SCHEMBL11324534 | 0.76 | MCL1 (0.57) | MCL1TTRKDM4ESMN1; SMN2 | |
| SCHEMBL4982792 | 0.74 | SIRT2 (0.47) | MCL1TTRCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11309294 | 0.74 | POLB (0.35) | MCL1CA12CA9 | |
| SCHEMBL11313409 | 0.73 | MCL1 (0.57) | MCL1TTRKDM4ECA12CA9 | |
| SCHEMBL11320518 | 0.73 | TTR (0.52) | MCL1TTRL3MBTL1 | |
| SCHEMBL6394892 | 0.71 | AKR1B1 (0.47) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL11311546 | 0.70 | MAPT (0.49) | MCL1KDM4ECA12CA9SMN1; SMN2 | |
| SCHEMBL11329000 | 0.70 | MAPT (0.50) | MCL1CSNK2A2CSNK2BCSNK2A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307020-A | REACTING AN 0-HYDROXYACETOPHENONE WITH A GLYOXYLIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4285965-A | FUNGICIDES AND INSECTICIDES FOR PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |
| EP-0000377-B1 | PROCESS FOR THE PREPARATION OF CHROMONE DERIVATIVES, NEW CHROMONE DERIVATIVES AND THEIR USE AS PLANT-PROTECTING AGENTS | BAYER AG (DE) | 1981-01-21 | — | — | EP | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |