Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 18/20 | 0.51 |
| ▸ | CA2 | P00918 | 18/20 | 0.51 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087447 | 0.89 | CA1 (0.61) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11090797 | 0.78 | CA1 (0.51) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11090781 | 0.78 | CA1 (0.51) | CA1CA2CA7CA13CA12 | |
| SCHEMBL940346 | 0.76 | CA1 (0.59) | CA1CA2CA7CA13CA12 | |
| SCHEMBL31018987 | 0.76 | CA1 (0.59) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11079988 | 0.75 | CA1 (0.57) | CA1CA2CA7CA13 | |
| SCHEMBL11301698 | 0.75 | CA1 (0.57) | CA1CA2CA7CA13 | |
| SCHEMBL11079985 | 0.75 | CA1 (0.57) | CA1CA2CA7CA13 | |
| SCHEMBL11084329 | 0.75 | CA2 (0.47) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11088267 | 0.75 | CA1 (0.41) | CA1CA2CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56123914-A | — | — | None | — | — | JP | disclosed |
| JP-S56123914-A | REMEDY FOR HYPERTENSION | YOSHITOMI PHARMACEUT IND LTD | 1981-09-29 | — | — | JP | disclosed |