Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088267 | 0.85 | CA1 (0.41) | CA2MMP2KDM4ELMNAGLA | |
| SCHEMBL11084537 | 0.82 | CA2 (0.44) | CA2KDM4ELMNAGLAMAPT | |
| SCHEMBL11084531 | 0.82 | CA2 (0.44) | CA2KDM4ELMNAGLAMAPT | |
| SCHEMBL31069941 | 0.81 | CA2 (0.66) | CA2MMP2KDM4ELMNAGLA | |
| SCHEMBL7373956 | 0.78 | KMT2A (0.65) | KMT2AACE | |
| SCHEMBL11087447 | 0.78 | CA1 (0.61) | CA2CA1CA7CA13CA12 | |
| SCHEMBL11309967 | 0.75 | CA1 (0.51) | CA2MMP2CA1CA7CA13 | |
| SCHEMBL11122413 | 0.73 | CA2 (0.62) | CA2KDM4ELMNAGLAMAPT | |
| SCHEMBL7373155 | 0.71 | KMT2A (0.57) | KMT2AACE | |
| SCHEMBL11174620 | 0.71 | PARP1 (0.50) | LMNAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | disclosed |