Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145892 | 0.90 | ALDH1A1 (0.60) | ALDH1A1MAPK1NCOA1NCOA3MCL1 | |
| SCHEMBL9780765 | 0.86 | LTA4H (0.50) | ALDH1A1MAPK1LTA4HTSHRNCOA1 | |
| SCHEMBL11328112 | 0.79 | MAPK1 (0.42) | ALDH1A1MAPK1LTA4HTSHRNCOA1 | |
| SCHEMBL30317545 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPK1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1642224 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPK1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2203394 | 0.78 | NCOA1 (0.55) | ALDH1A1MAPK1LTA4HTSHRNCOA1 | |
| SCHEMBL28039455 | 0.78 | KDM4E (0.47) | ALDH1A1MAPK1NCOA1NCOA3MAPT | |
| SCHEMBL30822034 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LTA4HTSHRNCOA1NCOA3 | |
| SCHEMBL8005050 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1LTA4HTSHRNCOA1 | |
| SCHEMBL3786852 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LTA4HTSHRNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |