SCHEMBL3786852

SCHEMBL3786852

Nc1cccc(-c2ccccc2)c1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 1/20 0.54
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
MAOB P27338 1/20 0.42
MAOA P21397 1/20 0.42
LTA4H P09960 1/20 0.41
TSHR P16473 1/20 0.41
GSTP1 P09211 1/20 0.40
MAP4K4 O95819 1/20 0.40
CSF1R P07333 1/20 0.40
FGFR1 P11362 1/20 0.40
PDGFRA P16234 1/20 0.40
LTK P29376 1/20 0.40
KDR P35968 1/20 0.40
MAPK8 P45983 1/20 0.40
CSNK1A1 P48729 1/20 0.40
LIMK1 P53667 1/20 0.40
CDK5 Q00535 1/20 0.40
ACVR1 Q04771 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30822034 1.00 ALDH1A1 (0.54) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL5745573 0.93 ALDH1A1 (0.45) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL3806719 0.91 NCOA1 (0.53) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL25135313 0.91 NCOA1 (0.62) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL3785402 0.88 MAOB (0.53) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL25135314 0.88 MAOB (0.58) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL6681919 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL3786946 0.86 ALDH1A1 (0.52) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL9780765 0.86 LTA4H (0.50) ALDH1A1HSD17B10NCOA1NCOA3MAOB
SCHEMBL29164962 0.85 NCOA1 (0.44) ALDH1A1HSD17B10NCOA1NCOA3MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104878130-B A kind of complex function amino resin tanning agent and preparation method thereof 兄弟科技股份有限公司 2017-03-29 CN claimed
CN-112011308-B Composition, adhesive material, adhesive layer, adhesive sheet, copper foil, copper-clad laminate, wiring board, and method for producing same 荒川化学工业株式会社 2023-05-30 CN disclosed
CN-106916306-B Resin composition, and insulating substrate and circuit board comprising same 张绮兰 2020-11-17 CN disclosed
CN-104845011-B A kind of EVA composition, foam and the method for preparing foamed material with it 陈龙飞 2019-07-19 CN disclosed
CN-104893300-B High-damping composition, its preparation method and product therefrom 鞍山市金钢碳纤维复合材料有限公司 2018-01-16 CN disclosed
CN-105647446-B Alone trademark adhesive of express delivery and preparation method thereof 如皋市嘉好热熔胶有限公司 2017-09-15 CN disclosed
CN-105038441-B One pack system high abrasion, high adhesion force plastic paint 上海祥水汽车零配件有限公司 2017-08-15 CN disclosed
CN-104893449-B Blended PTFE composition and paint for porous filter base material 上海超高工程塑料有限公司 2017-05-03 CN disclosed
CN-104878130-B A kind of complex function amino resin tanning agent and preparation method thereof 兄弟科技股份有限公司 2017-03-29 CN disclosed
CN-106365345-A Treatment method of oil and gas field fracturing flow-back liquid 河南油田工程咨询有限公司 2017-02-01 CN disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
US-7411014-B2 Stabilization of polyetherimide sulfones SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-12 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
US-20070190882-A1 Laminate and method GENERAL ELECTRIC 2007-08-16 US disclosed
US-20060281840-A1 Stabilization of polyetherimide sulfones SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-12-14 US disclosed
US-20060270825-A1 Precipitative process to prepare polyimides SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-11-30 US disclosed
EP-1639044-A2 POLYIMIDE RESIN WITH REDUCED MOLD DEPOSIT GENERAL ELECTRIC COMPANY (US) 2006-03-29 EP disclosed
US-6919422-B2 Polyimide resin with reduced mold deposit GENERAL ELECTRIC COMPANY (US) 2005-07-19 US disclosed
WO-2004113446-A2 POLYIMIDE RESIN WITH REDUCED MOLD DEPOSIT GENERAL ELECTRIC COMPANY (US) 2004-12-29 WO disclosed
US-20040260055-A1 Polyimide resin with reduced mold deposit GENERAL ELECTRIC COMPANY 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ALDH1A1 4339/4885HSD17B10 1100/4885NCOA1 2120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.