Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17840160 | 0.95 | KIF11 (0.68) | KIF11ALDH1A1TSHRBACE1TOP1 | |
| SCHEMBL8025255 | 0.93 | KIF11 (0.65) | KIF11ALDH1A1TSHRBACE1TOP1 | |
| SCHEMBL163728 | 0.87 | KIF11 (1.00) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| SCHEMBL8025260 | 0.87 | KIF11 (0.65) | KIF11ALDH1A1TSHRBACE1TOP1 | |
| Ammonia Solution, Strong SCHEMBL21809401 | 0.85 | KIF11 (0.95) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| Water SCHEMBL7382449 | 0.85 | KIF11 (0.95) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| SCHEMBL27887943 | 0.85 | KIF11 (0.95) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| Nitrogen SCHEMBL261370 | 0.83 | KIF11 (0.90) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| Hydrazine SCHEMBL27541145 | 0.83 | KIF11 (0.90) | KIF11ALDH1A1TSHRBACE1SCN2A | |
| SCHEMBL27781322 | 0.82 | KIF11 (0.58) | KIF11ALDH1A1TSHRBACE1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101709023-B | 2,2',6,6'-tetrahydroxy-3,3',5,5'-tetra-substituted biphenyl ligand and synthesis method thereof | NIPPON CHEMICAL IND | 2013-06-12 | — | — | CN | disclosed |
| CN-101709023-A | 2,2',6,6'-tetrahydroxy-3,3',5,5'-tetra-substituted biphenyl ligand and synthesis method thereof | NIPPON CHEMICAL IND | 2010-05-19 | — | — | CN | disclosed |
| US-4339608-A | BUTANOL AND BUTANAL, COBALT, IODINE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-07-13 | — | — | US | disclosed |