Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310344 | 0.87 | KIF11 (0.77) | KIF11ALDH1A1BACE1TSHRMAPT | |
| SCHEMBL31625453 | 0.83 | KIF11 (0.59) | KIF11ALDH1A1BACE1TSHRENPP1 | |
| SCHEMBL17840160 | 0.83 | KIF11 (0.68) | KIF11ALDH1A1BACE1TSHRTOP1 | |
| SCHEMBL5702375 | 0.82 | KIF11 (0.47) | KIF11ALDH1A1BACE1TSHRENPP1 | |
| SCHEMBL8662997 | 0.81 | PTGES2 (0.51) | KIF11BACE1POLB | |
| Bromide SCHEMBL3137328 | 0.81 | KIF11 (0.45) | KIF11ALDH1A1BACE1TSHRENPP1 | |
| SCHEMBL8025255 | 0.81 | KIF11 (0.65) | KIF11ALDH1A1BACE1TSHRTOP1 | |
| SCHEMBL3140032 | 0.80 | KIF11 (0.46) | KIF11ALDH1A1BACE1ENPP1MAPT | |
| SCHEMBL15069341 | 0.80 | ALDH1A1 (0.50) | ALDH1A1BACE1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL163728 | 0.80 | KIF11 (1.00) | KIF11ALDH1A1BACE1TSHRSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000045435-A1 | POLYIMIDES USED AS MICROELECTRONIC COATINGS | THE UNIVERSITY OF AKRON (US) | 2000-08-03 | — | — | WO | disclosed |