Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14673728 | 0.77 | MAPT (0.41) | MAPTTSHRHPGDSMN1; SMN2NQO1 | |
| SCHEMBL11556458 | 0.76 | CYP1A2 (0.41) | TSHRHPGDALDH1A1ALOX15KMT2A | |
| SCHEMBL16009860 | 0.74 | MAOA (0.42) | MAPTTSHRHPGDSMN1; SMN2KDM4E | |
| SCHEMBL13563036 | 0.73 | MAPT (0.38) | MAPTTSHRNQO1ALDH1A1IDO1 | |
| SCHEMBL10725852 | 0.73 | PDGFRB (0.39) | MAPTTSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28859068 | 0.73 | MAPT (0.43) | MAPTCA1CA2 | |
| SCHEMBL1128095 | 0.72 | NQO1 (0.56) | MAPTLMNAHPGDSMN1; SMN2NQO1 | |
| SCHEMBL10607942 | 0.72 | MAPT (0.43) | MAPTTSHRHPGDSMN1; SMN2NQO1 | |
| SCHEMBL10734164 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL14673501 | 0.71 | MAPT (0.46) | MAPTTSHRNQO1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252895-A | 1,3,4-THIADIAZOLE COMPOUND | ORIENTAL PHOTO INDUSTRIAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |