Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311158 | 0.82 | ACMSD (0.46) | ALDH1A1TDP1MAPK1CDC25BATM | |
| SCHEMBL11312016 | 0.78 | CDC25B (0.52) | ALDH1A1TDP1MAPK1CDC25BATM | |
| SCHEMBL420969 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPK1KDM4EMAPT | |
| SCHEMBL29165406 | 0.76 | AKT1 (0.48) | ALDH1A1TDP1MAPK1SIRT1SLC6A2 | |
| SCHEMBL11313049 | 0.73 | HTT (0.44) | ALDH1A1TDP1MAPK1SLC6A4SLC6A3 | |
| SCHEMBL11322841 | 0.70 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPK1CDC25BATM | |
| SCHEMBL11724363 | 0.70 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK1CDC25BATM | |
| SCHEMBL1482567 | 0.70 | POLB (0.74) | ALDH1A1TDP1SIRT1POLBKDM4E | |
| SCHEMBL29888792 | 0.70 | POLB (0.74) | ALDH1A1TDP1SIRT1POLBKDM4E | |
| SCHEMBL9625706 | 0.69 | AKR1C3 (0.59) | ALDH1A1TDP1SIRT1POLBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304898-A | HEAT RESIST METAL WIRE COATINGS | INSTITUT FRANCAIS DU PETROLE (FR) | 1981-12-08 | — | — | US | disclosed |