SCHEMBL420969

SCHEMBL420969

O=CC(=O)c1ccccc1C(=O)C=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.59
MAPK1 P28482 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALOX15 P16050 2/20 0.48
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
GAA P10253 2/20 0.43
AKR1C3 P42330 1/20 0.42
KDM4E B2RXH2 3/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HMGB1 P09429 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
NAPRT Q6XQN6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8584627 0.90 ALDH1A1 (0.67) ALDH1A1MAPK1TDP1ALOX15AKR1C3
SCHEMBL21616631 0.88 ALDH1A1 (0.52) ALDH1A1MAPK1TDP1ALOX15GAA
SCHEMBL11312016 0.86 CDC25B (0.52) ALDH1A1MAPK1TDP1ALOX15CES2
SCHEMBL1839194 0.85 KDM4E (0.57) ALDH1A1MAPK1TDP1ALOX15GAA
SCHEMBL295344 0.85 CES2 (0.62) ALDH1A1MAPK1TDP1ALOX15CES2
SCHEMBL293634 0.83 CES2 (0.60) ALDH1A1MAPK1TDP1CES2CES1
SCHEMBL3728578 0.83 MAPT (0.58) ALDH1A1MAPK1TDP1ALOX15GAA
SCHEMBL1697526 0.83 GPR52 (0.50) ALDH1A1MAPK1TDP1KDM4EHPGD
Water SCHEMBL29955657 0.83 CES2 (0.60) ALDH1A1MAPK1TDP1ALOX15CES2
SCHEMBL29883975 0.83 GPR52 (0.50) ALDH1A1MAPK1TDP1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325016-A Schiff base amorphous porous organic polymer and preparation method and application thereof 青海师范大学 2024-07-12 CN claimed
CN-118307627-A Epoxy ketone-containing cyclopeptide compound, and preparation method and application thereof 浙大城市学院 2024-07-09 CN claimed
CN-118298903-A Protease screening method based on computer simulation technology and application of protease screening method in preparation of collagen tripeptide 广东亿超生物科技有限公司 2024-07-05 CN claimed
CN-115836681-B O-phthalaldehyde disinfectant and preparation method thereof 利康医药科技江苏有限公司 2024-07-02 CN claimed
CN-118225900-A Determination analysis method for phthalic aldehyde content in lacidipine 上海奥博生物医药股份有限公司 2024-06-21 CN claimed
CN-118185603-A Degradable high-temperature-resistant high-pressure-resistant knotted temporary plugging agent and preparation method and application thereof 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-118130589-A Application of advanced glycosylation end product in food allergen detection and allergen-sugar complex sensitization evaluation method 中国海洋大学 2024-06-04 CN claimed
CN-118104653-A Low-foam low-odor phthalic dicarboxaldehyde disinfectant and preparation method thereof 山东安捷高科消毒科技有限公司 2024-05-31 CN claimed
CN-118108916-A Covalent organic polymer photocatalyst, and preparation method and application thereof 湖南大学 2024-05-31 CN claimed
CN-118084751-A Preparation process and application of phthalaldehyde Schiff base compound 酒泉亚佳化学有限公司 2024-05-28 CN claimed
CN-1181369-A Process for purification of O-phthalaldehyde CHEMIE LINZ GMBH (AT) 1998-05-13 CN claimed
CN-1161044-A Process for preparing aqueous amine oxide solutions CHEMIEFASER LENZING AG (AT) 1997-10-01 CN claimed
CN-1125430-A The use of dialdehydes and acetals thereof for inhibiting decomposition of peroxide in the production and the treatment of recycled fiber pulp and other fiber pulp CELLKEMSERVICE OY (FI) 1996-06-26 CN claimed
EP-0681223-A1 Polyimide-imine toner and developer compositions XEROX CORPORATION (US) 1995-11-08 EP claimed
US-5409793-A Polyimide-imine toner and developer compositions XEROX CORPORATION (US) 1995-04-25 US claimed
EP-0577734-A1 CONTROLLED-RELEASE SOLID PHASE ASSAY DEVICE INCLUDING ENCAPSULATED REAGENTS FOR DETECTING CHEMICAL SUBSTANCES MICRO RESEARCH, INC. (US) 1994-01-12 EP claimed
CN-1071146-A The method of control biofouling UNION CARBIDE CHEM PLASTIC (US) 1993-04-21 CN claimed
WO-1992017769-A1 CONTROLLED-RELEASE SOLID PHASE ASSAY DEVICE INCLUDING ENCAPSULATED REAGENTS FOR DETECTING CHEMICAL SUBSTANCES MICRO RESEARCH INC. (US) 1992-10-15 WO claimed
US-4100137-A Crosslinking of hydroxyl-containing polymers with polyaldehyde compounds POLYSAR LIMITED (CA) 1978-07-11 US claimed
US-4005053-A Polymer-oil-black masterbatch POLYSAR LIMITED (CA) 1977-01-25 US claimed