Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.68 |
| ▸ | AR | P10275 | 4/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311611 | 1.00 | PGR (0.68) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL11313619 | 1.00 | PGR (0.68) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL8499707 | 0.92 | HIF1A (0.68) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL8499697 | 0.92 | HIF1A (0.68) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL10891069 | 0.91 | HIF1A (0.64) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL10427927 | 0.91 | HIF1A (0.64) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL20709783 | 0.91 | HIF1A (0.64) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL10891061 | 0.91 | HIF1A (0.64) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL11432685 | 0.90 | HIF1A (0.58) | PGRARHIF1ACYP3A4NR3C1 | |
| SCHEMBL9627202 | 0.90 | HIF1A (0.59) | PGRARHIF1ACYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273770-A | CORTICOIDS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-06-16 | — | — | US | disclosed |
| EP-0004773-B1 | 17-BETA-THIOCARBOXYLIC ACID ESTERS OF 4-HALO-3-OXOANDROST-4-ENES, THEIR PHARMACEUTICAL USE AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4246346-A | ACTIVATING THE IMMOBILIZED MICROORGANISMS BY ADDING PEPTONE OR GLUCOSE TO THE REACTION MIXTURE | AKTIEBOLAGET FERMENTA (SE) | 1981-01-20 | — | — | US | disclosed |
| EP-0004773-A2 | 17-Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |
| US-3956349-A | TRIETHYL ORTHOACETATE, ACID CATALYST | SYNTEX (U.S.A.) INC. (US) | 1976-05-11 | — | — | US | disclosed |