SCHEMBL11311686

SCHEMBL11311686

Cc1cccc(C)c1N(CCCC(=O)O)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PTGIR P43119 2/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ S1PR1 P21453 3/20 0.39
▸ ABCB1 P08183 1/20 0.39
▸ F2 P00734 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.37
▸ KYAT1 Q16773 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321942 0.95 PTGIR (0.39) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11116763 0.95 HDAC6 (0.43) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11220562 0.92 HTT (0.44) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11325054 0.92 NPSR1 (0.39) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11314723 0.90 SMN1; SMN2 (0.43) NPSR1ALDH1A1KDM4ESMN1; SMN2POLB
SCHEMBL11317151 0.87 NPC1 (0.39) PTGIRNPSR1NPC1KDM4ERAB9A
SCHEMBL11314690 0.87 HDAC6 (0.39) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11428109 0.86 NPSR1 (0.42) PTGIRNPSR1ALDH1A1NPC1KDM4E
SCHEMBL11312940 0.85 PTGIR (0.46) PTGIRALDH1A1NPC1RAB9AL3MBTL1
SCHEMBL11315540 0.85 PTGIR (0.45) PTGIRALDH1A1NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240122210-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTION NATIVE MICROBIALS, INC. (US) 2024-04-18 — — US claimed
US-11910809-B2 Microbial compositions and methods of use for improving milk production NATIVE MICROBIALS, INC. (US) 2024-02-27 — — US claimed
US-20230139325-A1 IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS NATIVE MICROBIALS, INC. (US) 2023-05-04 — — US claimed
EP-4125413-A1 IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS Native Microbials, Inc. (US) 2023-02-08 — — EP claimed
US-20220287330-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTION NATIVE MICROBIALS, INC. (US) 2022-09-15 — — US claimed
US-4205088-A GASTROINTESTINAL DISORDERS, CARDIOVASCULAR DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-05-27 — — US claimed
US-4034111-A INTESTINAL SECRETION AND CARDIAC STIMULATION BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-07-05 — — US claimed
EP-3400285-B1 METHODS FOR IMPROVING MILK PRODUCTION BY ADMINISTRATION OF MICROBIAL CONSORTIA NATIVE MICROBIALS INC (US) 2025-10-29 — — EP disclosed
US-20240389619-A1 RUMINANT COMPOSITIONS NATIVE MICROBIALS, INC. (US) 2024-11-28 — — US disclosed
US-20240207331-A1 COMPOSITIONS AND METHODS FOR IMPROVING MILK YIELD AND MILK COMPOSITIONAL CHARACTERISTICS IN RUMINANTS WESTERN ALLIANCE BANK 2024-06-27 — — US disclosed
US-20240122210-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTION NATIVE MICROBIALS, INC. (US) 2024-04-18 — — US disclosed
US-11910809-B2 Microbial compositions and methods of use for improving milk production NATIVE MICROBIALS, INC. (US) 2024-02-27 — — US disclosed
US-11910808-B2 Ruminant compositions NATIVE MICROBIALS, INC. (US) 2024-02-27 — — US disclosed
US-20230139325-A1 IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS NATIVE MICROBIALS, INC. (US) 2023-05-04 — — US disclosed
EP-4125413-A1 IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS Native Microbials, Inc. (US) 2023-02-08 — — EP disclosed
US-20220287330-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTION NATIVE MICROBIALS, INC. (US) 2022-09-15 — — US disclosed
US-11291219-B2 Microbial compositions and methods of use for improving milk production NATIVE MICROBIALS, INC. (US) 2022-04-05 — — US disclosed
US-4250183-A GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1981-02-10 — — US disclosed
US-4205088-A GASTROINTESTINAL DISORDERS, CARDIOVASCULAR DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1980-05-27 — — US disclosed
US-4034111-A INTESTINAL SECRETION AND CARDIAC STIMULATION BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-07-05 — — US disclosed
Send feedback