Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMYD2 | Q9NRG4 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200220 | 0.84 | POLB (0.54) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL11178712 | 0.84 | POLB (0.55) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL11302230 | 0.83 | MCHR1 (0.60) | POLBMCHR1 | |
| SCHEMBL11198118 | 0.82 | POLB (0.54) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL11165965 | 0.82 | MCHR1 (0.55) | POLBTSHRHSD17B10MCHR1 | |
| SCHEMBL10356773 | 0.82 | MCHR1 (0.55) | POLBTSHRHSD17B10MCHR1 | |
| SCHEMBL11165531 | 0.82 | MCHR1 (0.55) | POLBTSHRHSD17B10MCHR1 | |
| SCHEMBL11441498 | 0.81 | MCHR1 (0.56) | POLBGAAMCHR1SMN1; SMN2 | |
| SCHEMBL11194691 | 0.80 | POLB (0.52) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL11442018 | 0.79 | ALDH1A1 (0.55) | POLBTSHRHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |