Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.48 |
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CBX7 | O95931 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114507 | 0.88 | TIMP3 (0.48) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL10791619 | 0.87 | TIMP3 (0.47) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL10792013 | 0.87 | TIMP3 (0.47) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL10943480 | 0.85 | TIMP3 (0.48) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL942276 | 0.84 | CASP6 (0.51) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL8417845 | 0.83 | TIMP3 (0.53) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL10945343 | 0.83 | TIMP3 (0.47) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL8109469 | 0.83 | TIMP3 (0.47) | CA1CA2TIMP3MEN1USP2 | |
| SCHEMBL11133315 | 0.82 | TIMP3 (0.45) | TIMP3MEN1USP2RECQLKMT2A | |
| SCHEMBL9697630 | 0.81 | NT5E (0.53) | TIMP3MEN1USP2RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263206-A | Reactive dyestuffs containing chlorine or fluorine substituents and one or more 1,3-dicyanobenzene radicals linked to the dyestuff at the 2-, 4- or 6-position | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4213899-A | FOR CELLULOSE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-22 | — | — | US | disclosed |