Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CBX7 | O95931 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948594 | 0.90 | NT5E (0.44) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL9723988 | 0.89 | CASP6 (0.48) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL8417845 | 0.89 | TIMP3 (0.53) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL10791619 | 0.87 | TIMP3 (0.47) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL11512263 | 0.87 | TIMP3 (0.68) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL1804480 | 0.86 | TIMP3 (0.51) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL9697630 | 0.86 | NT5E (0.53) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL8114507 | 0.86 | TIMP3 (0.48) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL10787792 | 0.86 | TIMP3 (0.48) | CASP6TIMP3KMT2AMEN1USP2 | |
| SCHEMBL10792013 | 0.85 | TIMP3 (0.47) | TIMP3KMT2AMEN1USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252278-A2 | Disinfecting agents and their use in disinfecting the skin and mucous membranes | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-01-13 | — | — | EP | claimed |
| EP-0045488-B1 | WATER-SOLUBLE FIBRE-REACTIVE COMPOUNDS AND THEIR USE IN FINISHING TEXTILES, AS WELL AS THE BETA-CHLOROETHYL-SULFONYL-METHYL-BENZOIC-ACID HALOGENIDES, AND THEIR USE AS A FIBRE-REACTIVE ANCHOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-19 | — | — | EP | claimed |
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | CLARIANT INTERNATIONAL LTD. (CH) | 2019-09-10 | — | — | US | disclosed |
| US-9834635-B2 | Polymers based on arcrylic, methacrylic or ethacrylic amidoalkyl sulfonic acid or salts and carboxyalky acrylate, methacrylate or ethacrylate or oligomers of said carboxy compounds | CLARIANT INTERNATIONAL LTD. (CH) | 2017-12-05 | — | — | US | disclosed |
| US-20170105910-A1 | UV FILTER CAPSULE | BASF SE (DE) | 2017-04-20 | — | — | US | disclosed |
| US-9295626-B2 | Compositions comprising isosorbide monoester and N-hydroxypyridones | CLARIANT INTERNATIONAL LTD. (CH) | 2016-03-29 | — | — | US | disclosed |
| US-8962796-B2 | Modified variant Bowman Birk protease inhibitors | DANISCO US INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 2014-12-18 | — | — | US | disclosed |
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-27 | — | — | US | disclosed |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | CLARIANT INTERNATIONAL LTD. (CH) | 2014-11-06 | — | — | US | disclosed |
| EP-0017768-A1 | Reactive dyestuffs and their use | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4134887-A | FIBER-REACTIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |
| US-4126609-A | AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-21 | — | — | US | disclosed |
| US-4089895-A | COUPLER FOR AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4066638-A | WATER-SOLUBLE FIBER REACTIVE PHENYL-AZO-NAPHTHYL DYESTUFFS CONTAINING TWO SULFO GROUPS IN THE PHENYL MOIETY | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
| US-4054559-A | Reactive disazo monohalogenotriazine dyestuffs | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-10-18 | — | — | US | disclosed |
| US-4049704-A | AZO REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4045428-A | Water-soluble reactive naphthylazonaphthyl dyestuffs | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140348763-A1 | COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP | ADH5, ADH1A, ADH1C | CASP6 1529/4885TIMP3 3903/4885KMT2A 4657/4885 |
| US-20170105910-A1 | UV FILTER CAPSULE | UROD, MITF, NISCH | CASP6 2724/4885TIMP3 3252/4885KMT2A 2903/4885 |
| US-10406135-B2 | Compositions containing isosorbide monoester and alcohols that contain at least one aromatic group | ADH5, ADH1A, ADH1C | CASP6 1529/4885TIMP3 3903/4885KMT2A 4657/4885 |
| US-20140343171-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTER AND N-HYDROXYPYRIDONES | HSD17B3, HSD3B1, HSD3B2 | CASP6 1509/4885TIMP3 3169/4885KMT2A 4640/4885 |
| US-20140369943-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE COMPOUNDS | FASN, HSD17B12, ELOVL3 | CASP6 1018/4885TIMP3 2103/4885KMT2A 4776/4885 |
| US-20140329870-A1 | COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES | HSD17B12, COASY, UGT2B17 | CASP6 1558/4885TIMP3 3861/4885KMT2A 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.