SCHEMBL1131332

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1132052	1.00	PTGS1 (0.41)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL1131591	0.91	CMKLR1 (0.39)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL1131587	0.91	CMKLR1 (0.39)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL12860095	0.89	CNR1 (0.46)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL1131969	0.89	CMKLR1 (0.41)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL1131971	0.89	CMKLR1 (0.41)	PTGS1PTGS2BTKALDH1A1KDM4E
	SCHEMBL1132086	0.88	HRH3 (0.41)	BTKCMKLR1HRH3
	SCHEMBL1131853	0.86	BTK (0.42)	BTKALDH1A1KDM4ECMKLR1HRH3
	SCHEMBL1131696	0.84	KDM4E (0.43)	BTKKDM4ECMKLR1HRH3KMT2A
	SCHEMBL1131589	0.82	CNR1 (0.40)	BTKKDM4ECMKLR1HRH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.