Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CMKLR1 | Q99788 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132025 | 0.90 | PTPN1 (0.43) | BTKPTPN1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL1132086 | 0.87 | HRH3 (0.41) | BTKCMKLR1HRH3 | |
| SCHEMBL1131332 | 0.86 | PTGS1 (0.41) | BTKCMKLR1HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL1132052 | 0.86 | PTGS1 (0.41) | BTKCMKLR1HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL1131587 | 0.85 | CMKLR1 (0.39) | BTKCMKLR1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1131591 | 0.85 | CMKLR1 (0.39) | BTKCMKLR1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1131589 | 0.83 | CNR1 (0.40) | BTKCMKLR1HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL1131696 | 0.83 | KDM4E (0.43) | BTKCMKLR1HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL1131586 | 0.81 | FABP3 (0.45) | BTKPTPN1CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL1131282 | 0.81 | FABP3 (0.45) | BTKPTPN1CHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |