Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 4/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131587 | 1.00 | CMKLR1 (0.39) | CMKLR1BTKPTGS1PTGS2GSK3B | |
| SCHEMBL1131332 | 0.91 | PTGS1 (0.41) | CMKLR1BTKPTGS1PTGS2GSK3B | |
| SCHEMBL1132052 | 0.91 | PTGS1 (0.41) | CMKLR1BTKPTGS1PTGS2GSK3B | |
| SCHEMBL1132022 | 0.90 | CMKLR1 (0.41) | CMKLR1BTKGSK3BBACE1KCNJ6 | |
| SCHEMBL1131853 | 0.85 | BTK (0.42) | CMKLR1BTKKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL1132086 | 0.84 | HRH3 (0.41) | CMKLR1BTKALOX5 | |
| SCHEMBL12860095 | 0.82 | CNR1 (0.46) | CMKLR1BTKPTGS1PTGS2GSK3B | |
| SCHEMBL1131279 | 0.81 | FABP3 (0.44) | CMKLR1BTKPTGS2GSK3BBACE1 | |
| SCHEMBL1131274 | 0.81 | FABP3 (0.44) | CMKLR1BTKPTGS2GSK3BBACE1 | |
| SCHEMBL1131696 | 0.81 | KDM4E (0.43) | CMKLR1BTKKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |