Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893096 | 0.89 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL10533316 | 0.86 | ALDH1A1 (0.49) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL11318676 | 0.83 | ADRA2A (0.47) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL10531764 | 0.81 | POLB (0.43) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL4811212 | 0.81 | KDM4E (0.38) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL10586953 | 0.81 | ALDH1A1 (0.44) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8913612 | 0.80 | POLB (0.38) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL11310255 | 0.77 | KDM4E (0.42) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL10587273 | 0.77 | ALDH1A1 (0.49) | KDM4EMAPTMEN1KMT2ATSHR | |
| SCHEMBL11326890 | 0.77 | IDH1 (0.37) | KDM4EMAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247456-A | Water-insoluble monoazo pyridone dye | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
| US-3957749-A | WATER-INSOLUBLE MONOAZO PYRIDINE DYES | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |