Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 3/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131371 | 1.00 | FAAH (0.37) | FAAHCMKLR1FFAR1FFAR4PTPN11 | |
| SCHEMBL1131841 | 0.92 | CMKLR1 (0.40) | CMKLR1FFAR1FFAR4CNR1CNR2 | |
| SCHEMBL1131843 | 0.92 | CMKLR1 (0.40) | CMKLR1FFAR1FFAR4CNR1CNR2 | |
| SCHEMBL1132056 | 0.89 | FAAH (0.37) | FAAHCMKLR1FFAR1FFAR4CNR1 | |
| SCHEMBL1131984 | 0.88 | FAAH (0.36) | FAAHCMKLR1FFAR1FFAR4BRD4 | |
| SCHEMBL1131983 | 0.88 | FAAH (0.36) | FAAHCMKLR1FFAR1FFAR4BRD4 | |
| SCHEMBL1131724 | 0.85 | PTPN11 (0.37) | FFAR1FFAR4PTPN11BRD4CNR1 | |
| SCHEMBL1132049 | 0.85 | PTPN11 (0.37) | FFAR1FFAR4PTPN11BRD4CNR1 | |
| SCHEMBL1132389 | 0.85 | CMKLR1 (0.40) | CMKLR1FFAR1FFAR4CNR1CNR2 | |
| SCHEMBL1131325 | 0.85 | CMKLR1 (0.40) | CMKLR1FFAR1FFAR4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |