Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 3/20 | 0.32 |
| ▸ | FABP4 | P15090 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131984 | 1.00 | FAAH (0.36) | FAAHGCGRCMKLR1ALDH1A1MAPK1 | |
| SCHEMBL1131445 | 0.93 | CMKLR1 (0.37) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131447 | 0.93 | CMKLR1 (0.37) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1132056 | 0.89 | FAAH (0.37) | FAAHGCGRCMKLR1FFAR1FFAR4 | |
| SCHEMBL1131367 | 0.88 | FAAH (0.37) | FAAHCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131371 | 0.88 | FAAH (0.37) | FAAHCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131986 | 0.82 | CMKLR1 (0.36) | FAAHGCGRCMKLR1FFAR1FFAR4 | |
| SCHEMBL1131767 | 0.81 | GCGR (0.39) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL4049827 | 0.81 | GCGR (0.39) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131843 | 0.80 | CMKLR1 (0.40) | CMKLR1FFAR1FFAR4FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |