Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314665 | 0.90 | NPC1 (0.57) | NPC1RAB9ACASP3SENP7TAS1R3 | |
| SCHEMBL11309788 | 0.89 | RAB9A (0.61) | NPC1RAB9ACASP3SENP7TAS1R3 | |
| SCHEMBL11174674 | 0.87 | JAK2 (0.57) | TAS1R3TAS1R1TAS1R2HDAC1SMN1; SMN2 | |
| SCHEMBL11172094 | 0.85 | TAS1R3 (0.65) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7572659 | 0.85 | KMT2A (0.69) | NPC1RAB9ACASP3SENP7TAS1R3 | |
| SCHEMBL11321129 | 0.84 | RAB9A (0.70) | NPC1RAB9ACASP3SENP7HDAC1 | |
| SCHEMBL10947015 | 0.82 | HDAC1 (0.62) | NPC1RAB9AHDAC1SMN1; SMN2KMT2A | |
| SCHEMBL11309849 | 0.82 | GAA (0.56) | TAS1R3TAS1R1TAS1R2HDAC1SMN1; SMN2 | |
| SCHEMBL11315847 | 0.82 | KCNK3 (0.60) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL10144733 | 0.81 | KMT2A (0.64) | NPC1RAB9ACASP3SENP7TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4031073-A | Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof | CIBA-GEIGY CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |