Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.63 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.63 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247348 | 0.92 | HTT (0.64) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL12047469 | 0.90 | LPAR1 (0.51) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL10028014 | 0.90 | LPAR1 (0.51) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL303128 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL4294185 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL4204833 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL7563995 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL4879843 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL8636551 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT | |
| SCHEMBL30910033 | 0.90 | LPAR1 (0.68) | LPAR1LPAR3LPAR2USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |