Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12047469 | 1.00 | LPAR1 (0.51) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047466 | 0.94 | LPAR1 (0.47) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047468 | 0.94 | LPAR1 (0.47) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047460 | 0.91 | LPAR1 (0.45) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL14616861 | 0.91 | HSD17B10 (0.50) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12047464 | 0.91 | LPAR1 (0.45) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL12301807 | 0.91 | LPAR1 (0.45) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL11314764 | 0.90 | LPAR1 (0.63) | LPAR1LPAR3LPAR2USP2TLR2 | |
| SCHEMBL12047457 | 0.90 | TSHR (0.43) | LPAR1LPAR3LPAR2TSHRUSP2 | |
| SCHEMBL8953351 | 0.89 | LPAR1 (0.46) | LPAR1LPAR3LPAR2TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110559-B2 | Hindered ester-based biodegradable linkers for oligonucleotide delivery | ENZON PHARMACEUTICALS, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100234444-A1 | HINDERED ESTER-BASED BIODEGRADABLE LINKERS FOR OLIGONUCLEOTIDE DELIVERY | ENZON PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-7625898-B2 | Posaconazole polymer conjugates and methods of treatment using posaconazole and polymer conjugates thereof | ENZON PHARMACEUTICALS, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20090202573-A1 | POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES | ENZON PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202573-A1 | POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES | PIGO, PHOSPHO1, PAICS | LPAR1 252/4885LPAR3 42/4885LPAR2 239/4885 |
| US-20100234444-A1 | HINDERED ESTER-BASED BIODEGRADABLE LINKERS FOR OLIGONUCLEOTIDE DELIVERY | VEGFA, DCLRE1B, MSN | LPAR1 530/4885LPAR3 302/4885LPAR2 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.