Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305655 | 0.88 | HPGD (0.40) | NPC1RAB9AHPGDACACBL3MBTL1 | |
| SCHEMBL11225292 | 0.88 | P2RX7 (0.47) | GAALMNAPOLBP2RX7L3MBTL1 | |
| SCHEMBL8445933 | 0.82 | HPGD (0.49) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL29657118 | 0.77 | HPGD (0.42) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL11314458 | 0.74 | P2RX7 (0.46) | MAPTLMNAPOLBP2RX7MEN1 | |
| SCHEMBL8446830 | 0.74 | NPC1 (0.48) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL8351698 | 0.72 | ACACB (0.49) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL9971091 | 0.71 | NPC1 (0.46) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL11326650 | 0.70 | P2RX7 (0.45) | NPC1RAB9AMAPTHPGDGAA | |
| SCHEMBL9615133 | 0.70 | P2RX7 (0.45) | RAB9AMAPTHPGDGAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56123957-A | — | — | None | — | — | JP | disclosed |
| JP-S56123957-A | N-DIMETHYLBENZYL-TERT-BUTYLACETAMIDE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING THE SAME AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1981-09-29 | — | — | JP | disclosed |