Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323039 | 0.86 | SMN1; SMN2 (0.46) | MAPTALDH1A1HTTHSD17B10LMNA | |
| SCHEMBL6553853 | 0.85 | KMT2A (0.42) | MAPTKMT2AMEN1TMPRSS15ALDH1A1 | |
| SCHEMBL7038319 | 0.84 | MEN1 (0.49) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL6555102 | 0.81 | TDP1 (0.46) | ALDH1A1LMNATSHRNPC1RAB9A | |
| SCHEMBL16863794 | 0.81 | ALDH1A1 (0.55) | MAPTKMT2AMEN1TMPRSS15ALDH1A1 | |
| SCHEMBL6555114 | 0.81 | ALDH1A1 (0.39) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL11331220 | 0.81 | KMT2A (0.47) | MAPTKMT2AMEN1TMPRSS15ALDH1A1 | |
| SCHEMBL7643085 | 0.80 | ALDH1A1 (0.59) | MAPTKMT2AMEN1ALDH1A1HSD17B10 | |
| SCHEMBL6553839 | 0.75 | ALDH1A1 (0.38) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL27536450 | 0.75 | CRHR1 (0.35) | MAPTKMT2AMEN1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |