Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318927 | 0.81 | MAPT (0.57) | MAPTCYP1A2CYP2C19LMNAKDM4E | |
| SCHEMBL28241923 | 0.73 | PLK4 (0.47) | MAPTCYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL15305720 | 0.69 | ADORA3 (0.50) | MAPTCYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL8219021 | 0.69 | NPC1 (0.58) | CYP1A2CYP2C19CYP2C9SMN1; SMN2L3MBTL1 | |
| SCHEMBL2179743 | 0.69 | MEN1 (0.61) | RAB9ANPC1BRAF | |
| SCHEMBL28736407 | 0.68 | CYP1A2 (0.64) | MAPTCYP1A2CYP2C19LMNAKDM4E | |
| SCHEMBL4037535 | 0.68 | FLT3 (0.44) | MAPTCYP1A2LMNAKDM4EHTT | |
| SCHEMBL2409063 | 0.67 | MAPT (0.62) | MAPTCYP1A2LMNAKDM4EHTT | |
| SCHEMBL8292660 | 0.66 | MITF (0.51) | MAPTLMNAHTTSMN1; SMN2POLB | |
| SCHEMBL18670793 | 0.66 | MAPT (0.50) | MAPTCYP1A2LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246410-A | BENZINDOLE DYES OF YELLOW AND RED | CIBA -GEIGY AKTIENGESELLSCHAFT (CH) | 1981-01-20 | — | — | US | disclosed |
| US-4189427-A | Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |