Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRAT | P43155 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311284 | 0.86 | MGAM (0.44) | CRATMGAMGAASIMGAM2 | |
| SCHEMBL7734523 | 0.85 | ALDH1A1 (0.46) | CRATMGAMGAASIMGAM2 | |
| SCHEMBL1405643 | 0.80 | CA12 (0.41) | CRATMGAMGAASIMGAM2 | |
| SCHEMBL23138664 | 0.74 | CRAT (0.35) | CRATMGAMGAASIMGAM2 | |
| SCHEMBL28243 | 0.71 | TSHR (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1144293 | 0.71 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1144274 | 0.71 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1144297 | 0.71 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL11306619 | 0.69 | MGAM (0.41) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28357259 | 0.69 | MGAM (0.41) | CRATMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275192-A | ANTINEOPLASTIC AND ANTIVIRAL ACTIVITY | G. D. SEARLE & CO. (US) | 1981-06-23 | — | — | US | disclosed |