Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 3/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | FABP3 | P05413 | 3/20 | 0.36 |
| ▸ | FABP4 | P15090 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131986 | 0.88 | CMKLR1 (0.36) | CMKLR1FFAR4FFAR1FABP3FABP4 | |
| SCHEMBL1132050 | 0.84 | CNR1 (0.38) | CMKLR1FFAR4FFAR1CNR1CNR2 | |
| SCHEMBL1131841 | 0.83 | CMKLR1 (0.40) | CMKLR1MARS1FFAR4FFAR1FABP3 | |
| SCHEMBL1131843 | 0.83 | CMKLR1 (0.40) | CMKLR1MARS1FFAR4FFAR1FABP3 | |
| SCHEMBL1131833 | 0.82 | MDM2 (0.47) | CMKLR1FABP3FABP4 | |
| SCHEMBL1131835 | 0.82 | MDM2 (0.47) | CMKLR1FABP3FABP4 | |
| SCHEMBL1131331 | 0.82 | FFAR4 (0.48) | CMKLR1FFAR4FFAR1FABP3FABP4 | |
| SCHEMBL1131259 | 0.81 | CMKLR1 (0.40) | CMKLR1MARS1FFAR4FFAR1FABP3 | |
| SCHEMBL1131325 | 0.81 | CMKLR1 (0.40) | CMKLR1MARS1FFAR4FFAR1FABP3 | |
| SCHEMBL1132389 | 0.81 | CMKLR1 (0.40) | CMKLR1MARS1FFAR4FFAR1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |