Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMKLR1 | Q99788 | 5/20 | 0.36 |
| ▸ | GCGR | P47871 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 3/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131567 | 0.88 | CMKLR1 (0.39) | CMKLR1GCGRFAAHFABP3FABP4 | |
| SCHEMBL1131447 | 0.85 | CMKLR1 (0.37) | CMKLR1GCGRFABP3FABP4FFAR4 | |
| SCHEMBL1131445 | 0.85 | CMKLR1 (0.37) | CMKLR1GCGRFABP3FABP4FFAR4 | |
| SCHEMBL1131984 | 0.82 | FAAH (0.36) | CMKLR1GCGRFAAHFABP3FABP4 | |
| SCHEMBL1131983 | 0.82 | FAAH (0.36) | CMKLR1GCGRFAAHFABP3FABP4 | |
| SCHEMBL1131833 | 0.78 | MDM2 (0.47) | CMKLR1FABP3FABP4 | |
| SCHEMBL1131835 | 0.78 | MDM2 (0.47) | CMKLR1FABP3FABP4 | |
| SCHEMBL1131977 | 0.76 | FABP3 (0.34) | CMKLR1GCGRFAAHFABP3FABP4 | |
| SCHEMBL1132019 | 0.75 | PTGS2 (0.40) | CMKLR1FAAHFABP3FABP4 | |
| SCHEMBL1132021 | 0.75 | PTGS2 (0.40) | CMKLR1FAAHFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |