Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131567 | 0.84 | CMKLR1 (0.39) | CNR1FFAR4FFAR1CNR2GCGR | |
| SCHEMBL1131291 | 0.84 | FFAR1 (0.39) | CNR1FFAR4FFAR1NR1H4MEN1 | |
| SCHEMBL1131288 | 0.84 | FFAR1 (0.39) | CNR1FFAR4FFAR1NR1H4MEN1 | |
| SCHEMBL1131301 | 0.81 | FFAR1 (0.39) | CNR1FFAR4FFAR1NR1H4MEN1 | |
| SCHEMBL1131302 | 0.81 | FFAR1 (0.39) | CNR1FFAR4FFAR1NR1H4MEN1 | |
| SCHEMBL1131417 | 0.81 | ALOX5 (0.43) | KMT2ALMNA | |
| SCHEMBL1131691 | 0.81 | ALOX5 (0.43) | KMT2ALMNA | |
| SCHEMBL1131724 | 0.81 | PTPN11 (0.37) | CNR1FFAR4FFAR1NR1H4PTPN11 | |
| SCHEMBL1132049 | 0.81 | PTPN11 (0.37) | CNR1FFAR4FFAR1NR1H4PTPN11 | |
| SCHEMBL1131931 | 0.79 | NR1H4 (0.40) | CNR1FFAR4FFAR1NR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |