Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 5/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25C | P30307 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000522 | 1.00 | RXFP1 (0.54) | RXFP1KMT2AMEN1CDC25BCDC25A | |
| SCHEMBL6814392 | 0.89 | RXFP1 (0.64) | RXFP1KMT2AMEN1CDC25BALDH1A1 | |
| SCHEMBL1900214 | 0.88 | RXFP1 (0.66) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL11290401 | 0.83 | CDC25B (0.58) | CDC25BCDC25ACDC25CNPC1RAB9A | |
| SCHEMBL10024769 | 0.83 | CDC25B (0.48) | KMT2AMEN1CDC25BCDC25ACDC25C | |
| SCHEMBL7014176 | 0.83 | KMT2A (0.49) | RXFP1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5516360 | 0.81 | ALDH1A1 (0.52) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL21387943 | 0.81 | RXFP1 (0.58) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29209745 | 0.81 | ALDH1A1 (0.51) | CDC25BCDC25ACDC25CNPC1RAB9A | |
| SCHEMBL9450358 | 0.80 | KMT2A (0.47) | RXFP1KMT2AMEN1CDC25BCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151674-A1 | QUINAZOLINE DERIVATIVE AS KRAS G12C MUTATION INHIBITOR | 深圳福沃药业有限公司 | 2023-08-17 | — | — | WO | disclosed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-4286962-A | Phthalocyanine reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl groups or amide groups | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-01 | — | — | US | disclosed |
| US-4267107-A | WATER SOLUBLE PHTHALOCYANINE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-12 | — | — | US | disclosed |