Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30000522 | 0.83 | RXFP1 (0.54) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL11315901 | 0.83 | RXFP1 (0.54) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL1900214 | 0.82 | RXFP1 (0.66) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL9450358 | 0.81 | KMT2A (0.47) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL7455097 | 0.81 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL8026725 | 0.81 | KMT2A (0.49) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL5351442 | 0.81 | PARP14 (0.54) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL6814392 | 0.80 | RXFP1 (0.64) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL8906402 | 0.79 | KMT2A (0.48) | KMT2AMEN1RXFP1ALDH1A1HPGD | |
| SCHEMBL11691985 | 0.79 | RXFP1 (0.48) | KMT2AMEN1RXFP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066246-B1 | NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING | OREAL (FR) | 2003-11-05 | — | — | EP | disclosed |
| US-6605124-B1 | Naphthol hair dyes for keratinous fibers | L'OREAL S.A. (FR) | 2003-08-12 | — | — | US | disclosed |
| EP-1066246-A1 | NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING | L'OREAL (FR) | 2001-01-10 | — | — | EP | disclosed |
| WO-2000043356-A1 | NOVEL CATIONIC COUPLERS AND THEIR USE FOR OXIDATION DYEING | L'OREAL (FR) | 2000-07-27 | — | — | WO | disclosed |
| US-4260558-A | Process for the preparation of aromatic aminohydroxy compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0001982-A1 | Process for preparing aromatic aminohydroxy compounds | BAYER AG (DE) | 1979-05-30 | — | — | EP | disclosed |