Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425344 | 0.88 | PABPC1 (0.41) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL13845511 | 0.86 | ALDH1A1 (0.41) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL10000303 | 0.84 | ESRRG (0.33) | RAB9AMAPTNPC1KDM4EMEN1 | |
| SCHEMBL11330897 | 0.78 | PABPC1 (0.53) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL11308089 | 0.77 | PABPC1 (0.48) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL13525220 | 0.77 | PABPC1 (0.59) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL2680700 | 0.76 | PABPC1 (0.56) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL9488788 | 0.73 | PABPC1 (0.47) | PABPC1RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL13845515 | 0.72 | MAPT (0.36) | RAB9AMAPTNPC1MAPK1MEN1 | |
| SCHEMBL126305 | 0.70 | PABPC1 (0.60) | PABPC1RAB9AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4046786-A | HAIR DYES | L'OREAL (FR) | 1977-09-06 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |