Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316014 | 0.88 | PABPC1 (0.42) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL11308089 | 0.79 | PABPC1 (0.48) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL11321519 | 0.79 | PABPC1 (0.52) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL13845511 | 0.75 | ALDH1A1 (0.41) | KMT2ANPC1MEN1MAPK1MAPT | |
| SCHEMBL2680700 | 0.75 | PABPC1 (0.56) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL10000303 | 0.73 | ESRRG (0.33) | KMT2ANPC1MEN1MAPTRAB9A | |
| SCHEMBL9488788 | 0.72 | PABPC1 (0.47) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL11626295 | 0.70 | — | — | |
| SCHEMBL11321038 | 0.70 | PABPC1 (0.42) | PABPC1ADRA2AADRA2BADRA2CNOS1 | |
| SCHEMBL126305 | 0.69 | PABPC1 (0.60) | PABPC1ADRA2AADRA2BADRA2CNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | claimed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |