Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522063 | 0.70 | AKT1 (0.43) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11291525 | 0.69 | CA2 (0.46) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL10758397 | 0.68 | CA2 (0.53) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL10244414 | 0.67 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1269530 | 0.67 | ALDH1A1 (0.41) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11105319 | 0.67 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11105312 | 0.67 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL2041571 | 0.65 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9212615 | 0.64 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL31462136 | 0.63 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288560-A | Process for foaming plastics | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |