Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11985682 | 0.93 | TSHR (0.59) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11330761 | 0.90 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11328998 | 0.89 | TSHR (0.69) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11314352 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4728781 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4732320 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4730460 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4728775 | 0.86 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL5706016 | 0.85 | KDM4E (0.63) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11427518 | 0.85 | TSHR (0.69) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287174-A | CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID | THE PROCTOR & GAMBLE COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4275059-A | IN COMBINATION WITH A DIPHOSPHONATE COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| US-4199576-A | DERIVATIVES OF SALICYCLIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| EP-0004686-A2 | Anti-ulcer composition | THE PROCTER & GAMBLE COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |