Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732320 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4728781 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL4728775 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11314352 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL27528077 | 0.99 | TSHR (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL1870045 | 0.94 | TSHR (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL9446603 | 0.94 | PTGS2 (0.75) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL12715080 | 0.94 | PTGS2 (0.75) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL22480224 | 0.92 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL11327527 | 0.91 | PTGS2 (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275059-A | IN COMBINATION WITH A DIPHOSPHONATE COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| US-4199576-A | DERIVATIVES OF SALICYCLIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-04-22 | — | — | US | claimed |
| CN-107530256-B | Topical sunscreen emulsions | 帝斯曼知识产权资产管理有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-9962369-B2 | Methods and compositions for transdermal delivery | SPRAYABLE HOLDINGS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20150250884-A1 | METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY | SPRAYABLE HOLDINGS, INC. | 2015-09-10 | — | — | US | disclosed |
| WO-2008043654-A2 | BLOND CLEAR TREATMENT | HENKEL AG & CO. KGAA (DE) | 2008-04-17 | — | — | WO | disclosed |
| US-4287174-A | CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID | THE PROCTOR & GAMBLE COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4275059-A | IN COMBINATION WITH A DIPHOSPHONATE COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| US-4199576-A | DERIVATIVES OF SALICYCLIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| EP-0004686-A2 | Anti-ulcer composition | THE PROCTER & GAMBLE COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250884-A1 | METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY | VDR, CYP27B1, TTPA | ALDH1A1 476/4885TSHR 1266/4885LMNA 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.