Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 12/20 | 0.44 |
| ▸ | RAB9A | P51151 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.44 |
| ▸ | RELA | Q04206 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316594 | 1.00 | MAPT (0.51) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL9007956 | 0.81 | MAPT (0.73) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11514038 | 0.81 | MAPT (0.47) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11316602 | 0.80 | RAB9A (0.50) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11327606 | 0.78 | MAPT (0.52) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11332706 | 0.78 | MAPT (0.52) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL8767775 | 0.75 | NPC1 (0.54) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11514766 | 0.70 | MAPT (0.46) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL11514759 | 0.70 | MAPT (0.46) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL31314986 | 0.69 | INSR (0.65) | MAPTMAPK1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292399-A | Cobalt (III) complex imaging compositions having improved photographic properties | EASTMAN KODAK COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4171221-A | NONSILVER PHOTOGTAPHY | EASTMAN KODAK COMPANY (US) | 1979-10-16 | — | — | US | disclosed |