Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.57 |
| ▸ | TMPRSS4 | Q9NRS4 | 8/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148682 | 0.89 | KCNMA1 (0.66) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL11230861 | 0.83 | NPC1 (0.61) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL18341191 | 0.83 | TMPRSS4 (0.75) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL8053234 | 0.82 | MEN1 (0.78) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL11683279 | 0.81 | P2RX1 (0.82) | KCNMA1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL17407572 | 0.81 | KMT2A (0.55) | KCNMA1TMPRSS4MEN1AURKANPC1 | |
| SCHEMBL30771727 | 0.80 | KCNMA1 (0.76) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL15026045 | 0.80 | KCNMA1 (0.76) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 | |
| SCHEMBL17295683 | 0.79 | RAB9A (0.60) | KCNMA1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL31238369 | 0.78 | TAS1R3 (0.86) | KCNMA1TAS1R3TAS1R1TAS1R2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956510-A | NESTING, CYLINDERS, LOOPS | BEALL NELSON J | 1976-05-11 | — | — | US | claimed |
| US-4252785-A | LOW MOLECULAR WEIGHT UREA-FORMALDEHYDE RESIN, GERMICIDE | HEXCEL CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-3956510-A | NESTING, CYLINDERS, LOOPS | BEALL NELSON J | 1976-05-11 | — | — | US | disclosed |