Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131417 | 1.00 | ALOX5 (0.43) | ALOX5KDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1131558 | 0.84 | ALOX5 (0.43) | ALOX5KDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1132050 | 0.81 | CNR1 (0.38) | KMT2ALMNA | |
| SCHEMBL1131254 | 0.80 | ALOX5 (0.42) | ALOX5KDM4ESMN1; SMN2KMT2ARAB9A | |
| SCHEMBL1131833 | 0.80 | MDM2 (0.47) | KDM4ESMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL1131835 | 0.80 | MDM2 (0.47) | KDM4ESMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL1131481 | 0.80 | PTPN1 (0.44) | ALOX5KDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1131573 | 0.80 | PTPN1 (0.44) | ALOX5KDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1131692 | 0.77 | PTPN1 (0.48) | ALOX5PRMT5ALDH1A1L3MBTL1 | |
| SCHEMBL1131416 | 0.77 | PTPN1 (0.48) | ALOX5PRMT5ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | claimed |
| EP-1663105-B1 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-02-16 | — | — | EP | disclosed |