Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316941 | 1.00 | NFE2L2 (0.47) | NFE2L2RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL11316940 | 1.00 | NFE2L2 (0.47) | NFE2L2RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL11314264 | 0.81 | NFE2L2 (0.44) | NFE2L2RAB9AMAPTCYP1B1RECQL | |
| SCHEMBL11314247 | 0.81 | NFE2L2 (0.44) | NFE2L2RAB9AMAPTCYP1B1RECQL | |
| SCHEMBL11314282 | 0.81 | NFE2L2 (0.44) | NFE2L2RAB9AMAPTCYP1B1RECQL | |
| SCHEMBL11407210 | 0.81 | RAB9A (0.48) | NFE2L2RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL11407212 | 0.81 | RAB9A (0.48) | NFE2L2RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL11407204 | 0.81 | RAB9A (0.48) | NFE2L2RAB9ASMN1; SMN2MAOBMAPT | |
| SCHEMBL11311798 | 0.81 | MAPT (0.45) | RAB9ASMN1; SMN2MAOBMAPTNPC1 | |
| SCHEMBL11311793 | 0.81 | MAPT (0.45) | RAB9ASMN1; SMN2MAOBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267359-A | Novel carboxylic acid esters | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |