Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311800 | 1.00 | MAPT (0.45) | MAPTMAOBNPC1RAB9AHDAC1 | |
| SCHEMBL11311793 | 1.00 | MAPT (0.45) | MAPTMAOBNPC1RAB9AHDAC1 | |
| SCHEMBL11325307 | 0.81 | NOS2 (0.47) | MAPTMAOBNPC1RAB9AHDAC1 | |
| SCHEMBL11325298 | 0.81 | NOS2 (0.47) | MAPTMAOBNPC1RAB9AHDAC1 | |
| SCHEMBL11325302 | 0.81 | NOS2 (0.47) | MAPTMAOBNPC1RAB9AHDAC1 | |
| SCHEMBL11316941 | 0.81 | NFE2L2 (0.47) | MAPTMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11316938 | 0.81 | NFE2L2 (0.47) | MAPTMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11316940 | 0.81 | NFE2L2 (0.47) | MAPTMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11325321 | 0.78 | SMPD2 (0.56) | MAPTNPC1RAB9AHDAC8HDAC6 | |
| SCHEMBL11390669 | 0.78 | ALDH1A1 (0.39) | MAPTMAOBLMNACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267359-A | Novel carboxylic acid esters | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
| US-4229368-A | Esters and thiolesters of unsaturated acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4204071-A | 4-Aryl-3-butenoic acids and lower alkyl esters | ZOECON CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |