Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906887 | 0.77 | TSHR (0.44) | TSHR | |
| SCHEMBL9015232 | 0.72 | — | — | |
| SCHEMBL9015189 | 0.69 | CYP1A2 (0.33) | — | |
| SCHEMBL3211235 | 0.67 | KDM4E (0.33) | TSHR | |
| SCHEMBL9138136 | 0.67 | HSD11B1 (0.32) | — | |
| SCHEMBL6839899 | 0.67 | SIRT2 (0.40) | TSHR | |
| SCHEMBL6704372 | 0.67 | SIRT2 (0.40) | TSHR | |
| Bicarbonate SCHEMBL10925671 | 0.66 | TSHR (0.58) | TSHR | |
| SCHEMBL3851227 | 0.66 | TSHR (0.50) | TSHR | |
| SCHEMBL12996650 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305823-A | MODIFIED WITH CYCLIC B-KETONIC ACIDS | CIBA-GEIGY CORPORATION (US) | 1981-12-15 | — | — | US | disclosed |
| US-4249000-A | SEMIPERMEABLE MEMBRANES FOR REVERSE OSMOSIS | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |