Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314305 | 0.91 | HPGD (0.45) | GAAHPGDEPHX2HDAC1HDAC6 | |
| SCHEMBL11227026 | 0.82 | EPHX2 (0.43) | EPHX2HDAC1HDAC6OPRM1HDAC3 | |
| SCHEMBL11319566 | 0.82 | HPGD (0.61) | GAAHPGDHDAC1HDAC6HDAC3 | |
| SCHEMBL11323521 | 0.81 | KDM4A (0.44) | EPHX2HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL11314879 | 0.80 | OPRD1 (0.43) | HDAC1HDAC6OPRD1KDM5APHF8 | |
| SCHEMBL11224743 | 0.79 | POLB (0.40) | GAAHDAC1HDAC6OPRD1OPRM1 | |
| SCHEMBL11312757 | 0.79 | KDM4A (0.43) | EPHX2HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL11321499 | 0.78 | BCHE (0.45) | EPHX2HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL11320955 | 0.77 | OPRD1 (0.44) | HDAC1HDAC6OPRD1OPRM1 | |
| SCHEMBL11315617 | 0.77 | PTGIR (0.39) | HPGDHDAC1HDAC6OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |