Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320266 | 0.93 | POLB (0.45) | POLBLMNAALDH1A1SMN1; SMN2GCGR | |
| SCHEMBL11314305 | 0.87 | HPGD (0.45) | ALDH1A1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL11314879 | 0.87 | OPRD1 (0.43) | GCGRHDAC6HDAC1OPRD1FOLH1 | |
| SCHEMBL11320955 | 0.87 | OPRD1 (0.44) | GCGRHDAC6HDAC1OPRD1OPRM1 | |
| SCHEMBL11237106 | 0.83 | PTGIR (0.46) | LMNAALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL11328953 | 0.81 | HDAC6 (0.44) | POLBLMNAALDH1A1SMN1; SMN2HDAC6 | |
| SCHEMBL11322309 | 0.81 | PTGIR (0.48) | LMNAALDH1A1KDM4ETSHRNPSR1 | |
| SCHEMBL11327056 | 0.81 | POLB (0.43) | POLBLMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11320450 | 0.81 | ALOX5 (0.45) | POLBLMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11227026 | 0.80 | EPHX2 (0.43) | HDAC6HDAC3HDAC1HDAC2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003056-B1 | N-SUBSTITUTED OMEGA-AMINOALKANOYL-OMEGA-AMINOALKANECARBOXYLIC ACIDS, THEIR APPLICATION AND PROCESS FOR THEIR PREPARATION, AND MEDICINES CONTAINING THESE COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0003056-A1 | N-substituted omega-aminoalkanoyl-omega-aminoalkanecarboxylic acids, their application and process for their preparation, and medicines containing these compounds | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-07-25 | — | — | EP | disclosed |