Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314879 | 0.96 | OPRD1 (0.43) | OPRD1GCGRGLP1RAGERHDAC1 | |
| SCHEMBL11224743 | 0.87 | POLB (0.40) | OPRD1GCGRHDAC1HDAC6FOLH1 | |
| SCHEMBL11320468 | 0.86 | AGER (0.50) | AGERHDAC1HDAC6TMEM97SIGMAR1 | |
| SCHEMBL11314305 | 0.85 | HPGD (0.45) | OPRD1HDAC1HDAC6OPRM1 | |
| SCHEMBL11320266 | 0.84 | POLB (0.45) | OPRD1GCGROPRM1 | |
| SCHEMBL11318737 | 0.83 | TMEM97 (0.42) | OPRD1GCGRGLP1RAGERHDAC1 | |
| SCHEMBL11224728 | 0.83 | TMEM97 (0.49) | AGERHDAC1HDAC6TMEM97SIGMAR1 | |
| SCHEMBL11324734 | 0.81 | PDE6D (0.45) | GCGRGLP1RHDAC1TMEM97SIGMAR1 | |
| SCHEMBL11317558 | 0.77 | GAA (0.44) | OPRD1HDAC1HDAC6OPRM1 | |
| SCHEMBL11322309 | 0.77 | PTGIR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |